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clustal w program bioedit version 7.0  (Bioedit Company)

 
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    Bioedit Company clustal w program bioedit version 7.0
    Clustal W Program Bioedit Version 7.0, supplied by Bioedit Company, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/clustal w program bioedit version 7.0/product/Bioedit Company
    Average 90 stars, based on 1 article reviews
    clustal w program bioedit version 7.0 - by Bioz Stars, 2026-06
    90/100 stars

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    Engineered Tm cells have the capability to ameliorate pathological MPS I hallmarks within the central nervous system (A) Representative histological images of human CD3 staining within brain tissue. Black arrows, CD3 immunopositive cells; gray arrows, astrocytes (top). Representative histological images of human IDUA within brain tissue (middle). Representative histological images of LAMP-1 staining within brain tissue. Black arrows, neurons; gray arrows, astrocytes (bottom). (B) Quantification of LAMP-1 immunohistochemistry within brain tissue samples ( n = 4 each cohort). (C) <t>Barnes</t> maze time to escape of heterozygous (black), untreated NSG-MPS I (red), and Tm cell-treated NSG-MPS I mice (blue) ( n = 9). Statistical analysis: one-way ANOVA (B), two-way ANOVA (C) ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, ∗∗∗∗ p < 0.0001.
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    Engineered Tm cells have the capability to ameliorate pathological MPS I hallmarks within the central nervous system (A) Representative histological images of human CD3 staining within brain tissue. Black arrows, CD3 immunopositive cells; gray arrows, astrocytes (top). Representative histological images of human IDUA within brain tissue (middle). Representative histological images of LAMP-1 staining within brain tissue. Black arrows, neurons; gray arrows, astrocytes (bottom). (B) Quantification of LAMP-1 immunohistochemistry within brain tissue samples ( n = 4 each cohort). (C) Barnes maze time to escape of heterozygous (black), untreated NSG-MPS I (red), and Tm cell-treated NSG-MPS I mice (blue) ( n = 9). Statistical analysis: one-way ANOVA (B), two-way ANOVA (C) ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, ∗∗∗∗ p < 0.0001.

    Journal: Molecular Therapy

    Article Title: Engineering memory T cells as a platform for long-term enzyme replacement therapy in lysosomal storage disorders

    doi: 10.1016/j.ymthe.2024.09.033

    Figure Lengend Snippet: Engineered Tm cells have the capability to ameliorate pathological MPS I hallmarks within the central nervous system (A) Representative histological images of human CD3 staining within brain tissue. Black arrows, CD3 immunopositive cells; gray arrows, astrocytes (top). Representative histological images of human IDUA within brain tissue (middle). Representative histological images of LAMP-1 staining within brain tissue. Black arrows, neurons; gray arrows, astrocytes (bottom). (B) Quantification of LAMP-1 immunohistochemistry within brain tissue samples ( n = 4 each cohort). (C) Barnes maze time to escape of heterozygous (black), untreated NSG-MPS I (red), and Tm cell-treated NSG-MPS I mice (blue) ( n = 9). Statistical analysis: one-way ANOVA (B), two-way ANOVA (C) ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, ∗∗∗∗ p < 0.0001.

    Article Snippet: The Barnes maze with AnyMaze (San Diego Instrument) program, version 7.0, was used to assess spatial learning and memory.

    Techniques: Staining, Immunohistochemistry